This call supports research that explores how AI is reshaping labour markets, productivity, and inequality across Africa, supporting policy makers to ensure AI works for everyone, especially the most vulnerable. We invite concept notes that explore the socio-economic impacts of AI in African LMICs, with a focus on differential impacts, inequality and marginalized populations. Projects should address key knowledge gaps and generate evidence to guide responsible AI policies. Research should align with one or more of the following themes: labour and livelihoods: how AI is transforming labour markets and employment, especially for youth and informal workers. productivity and economic transformation: the role of AI in reshaping sectors and supporting inclusive growth. poverty and inequality: risks of exclusion and unequal benefit distribution across demographic groups. global inequality and AI colonialism: power imbalances in AI development and strategies for local innovation.